11:00am-12:00pm Eastern Time (US)
Hosted by the HLH Steering Committee

TOPIC: COVID-19 and the host immune response/inflammatory phenotypes

Steven M. Holland, MD
National Institute of Allergy and Infectious Diseases
National Institutes of Health

Title of Presentation:
Who gets sick from COVID-19 and why?

Steven M. Holland, M.D., is the Director of the Division of Intramural Research (DIR) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH). As Director, Dr. Holland provides overall executive direction and scientific leadership for the Division’s basic and clinical research activities. Prior to becoming Director, DIR, NIAID, Dr. Holland served NIAID as Chief of the Laboratory of Clinical and Infectious Diseases (LCID). Dr. Holland continues to lead a program in NIAID as chief of its Immunopathogenesis Section in the Laboratory of Clinical Immunology and Microbiology. Dr. Holland is the author of more than 500 publications, a member of the National Academy of Medicine and an NIH Distinguished Investigator.  He has received the Infectious Diseases Society of America’s Walter E. Stamm Mentor Award, the American College of Physicians Award for Science, the Boyle Scientific Achievement Award of the Immune Deficiency Foundation, the American Society for Microbiology Abbott Award, the Erwin Neter Award of the Association of Medical Laboratory Immunologists, and the NIH Distinguished Clinical Teacher Award, among other awards. He received his B.A. degree from St. John's College in Annapolis, Maryland, in 1979 and his M.D. degree from the Johns Hopkins University School of Medicine in 1983.  He remained at Johns Hopkins for his internal medicine residency, chief residency, and fellowship in infectious diseases.  He came to NIAID in 1989 to study the molecular biology of HIV, and in 1991 moved to the Laboratory of Host Defenses, NIAID, to study phagocytes and phagocyte immunodeficiencies. In 2004, he became chief of LCID, NIAID, a position he held until his appointment as Director, DIR in July 2016.

Elizabeth Whittaker, PhD DTM&H MRCPCH
Imperial College London

Title of Presentation:
Paediatric inflammatory multi system syndrome, temporally associated with SARS-CoV-2 (PIMS-TS)

Dr Elizabeth Whittaker graduated from Trinity College Dublin, Ireland and following clinical experience in Dublin and Brisbane, Australia, moved to London. Here she trained as a pediatrician and was successfully awarded an academic clinical fellowship in pediatric infectious diseases in 2006. The nine-month research period associated with this fellowship allowed her to develop her interest in pediatric infectious diseases and involved a couple of research projects on tuberculosis biomarkers and interferon gamma release assays (IGRA). She completed the Gorgas Diploma Course in clinical tropical medicine in Peru and was awarded a DTM&H in 2009. 

Dr Whittaker completed her Wellcome Trust funded PhD project ‘Immune responses to mycobacteria; the role of age and disease severity’ in 2014, based between Imperial College London and the University of Cape Town in South Africa. She completed her pediatric training in 2016, combining clinical and research experience as an NIHR-funded academic clinical lecturer. 

Dr Whittaker is the pediatric specialty co-lead for the North West London Clinical Research Network. In this role, she leads the development of local clinical research network activity in pediatrics, encouraging local clinicians to participate in NIHR clinical research network portfolio studies. She is the secretary of the British Paediatric Allergy, Infection and Immunity Group (BPAIIG) and on the steering committee of the British Association of Paediatric TB (BAPT). She is the co-lead for high consequence infectious diseases (HCID) in children at Imperial and is on the RCPCH expert advisory group for COVID 19. 

Dr Whittaker has a strong interest in teaching and training and currently is the quality adviser to the pediatric allergy, immunology and infectious diseases CSAC committee at the Royal College of Paediatrics and Child Health.

Please Note: This webinar will be open to and intended for Medical Professionals only.  
Patients and families are encouraged to connect with the Histiocytosis Association for information on upcoming patient and family-focused webinars.

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The Histiocyte Society is a nonprofit organization of more than 200 physicians and scientists from around the world committed to improving the lives of patients with histiocytic disorders by conducting clinical and laboratory research into the causes and treatment of this disease.

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