Poulikos Poulikakos, PhD
Dr. Poulikakos received his Ph.D. in Biology in 2002 from the School of Biology, University of Athens, Greece and he subsequently pursued postdoctoral training on cancer biology and signaling, first in Dr. Joseph Testa’s laboratory, at the Fox Chase Cancer Center in Philadelphia, and subsequently in Dr. Neal Rosen’s laboratory, at Memorial Sloan Kettering Cancer Center (2006-2012) in New York. Since 2012 he is an Assistant Professor in the Department of Oncological Sciences and in the Department of Dermatology at the Icahn School of Medicine at Mount Sinai in New York.
Dr Poulikakos's research is focused on investigating mechanisms of growth factor signaling regulation and of tumor response to pharmacologic targeting of its components using small molecule inhibitors. During his postdoctoral training, he elucidated mechanisms of action of RAF inhibitors and identified mechanisms of clinical resistance to these drugs (Poulikakos, et. al., Nature, 2010, 2011). As an Assistant Professor, Dr. Poulikakos research program builds logically on his previous work and is directed towards elucidating mechanisms of oncogenic signaling regulation to develop more effective pharmacologic therapeutic strategies in cancer (Karoulia et al., Cancer Cell, 2016, KAroulia et al., Nat Rev Cancer, 2017, Ahmed et al., Cell Reports, 2019).
He has received a number of fellowships and awards, including the Sidney Kimmel Award for Cancer Research, The Society of Melanoma Research Young Investigator Award, as well as awards from the Melanoma Research Alliance, the Melanoma Research Foundation, The Dermatology Foundation and the Harry J. Lloyd Charitable Trust, among others.