I anticipate that you have all seen the recent JAMA report on 138 patient with nCoV (JAMA.2020.1585, published online 07FEB2020) .
In my opinion, while the report does not detail all of necessary data on the patients to optimally assess for hyperinflammation, the relatively short duration of hospitalization (7-14 days), rise in ANC in the ICU patients (although note steroid administration),median age for ICU patients was 67 and lack of other classic HLH-94 or H Score elements do not strongly support HLH as a part of the pathophysiology.
The SOFA score, as that is not specific for sepsis in the setting of proven HLH, is difficult to interpret.
Note that 72% of ICU patients received steroids, doses not specified.
I support education on HLH and continued reasonable vigilance for HLH via prospective data collection and expert consultation.
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